Join us on our mission to create the next generation of DNA synthesis. We are located in Berkeley and are currently looking for:
A microfluidics engineer to lead the development of our hardware platform
An enzymologist with experience characterizing DNA-processing enzymes
A chemist with experience synthesizing dNTP analogs
Daniel Arlow, CEO
PhD, UC Berkeley
Dan received his PhD from the University of California, Berkeley for his work in Jay Keasling’s lab developing new technologies for the de novo synthesis of DNA. Previously, he was a Scientific Associate at D.E. Shaw Research, where he studied the biophysical properties of G protein-coupled receptors, including how drugs bind and modulate their activity. Dan began his scientific career at MIT, where he earned dual S.B. degrees in Math with Computer Science and Biology, and developed computation tools for the analysis of regulation of gene expression in Vamsi Mootha’s lab at the Broad Institute of MIT and Harvard. He has co-authored over 20 scientific publications, including papers in Nature, Science, Cell, PNAS, and Nature Biotechnology that have been cited over 5,000 times in aggregate, and is a co-inventor of two patents.
Sebastian Palluk, CTO
PHd student, TU Darmstadt
Sebastian received a Bachelor's degree in Biology and a Master's degree in Biomolecular Engineering from Darmstadt University of Technology. His Master's thesis research was a computational investigation of the compatibility of Terminal Deoxynucleotidyl Transferase (TdT) with reversible Terminator Nucleotides (RTdNTPs) for de novo DNA synthesis. Sebastian joined Lawrence Berkeley Lab's Joint BioEnergy Institute in 2015, where he teamed up with Dan to develop the first demonstration of a practical enzymatic de novo DNA synthesis method, reported in Nature Biotechnology.
Jared Ellefson, Head of Protein Engineering
PHd, UT Austin
Jared received his PhD from the University of Texas at Austin for developing generalized techniques for the in vitro directed evolution of enzymes and pathways. He has over 15 peer reviewed publications in world class journals, including: Science, Nature, and Nature Biotechnology. He has led the development of improved enzymes for RNA transcription, amino-acyl tRNA synthetases, small molecule biosensors, and metabolic pathways. Of note, Jared developed a technique for the high-throughput evolution of thermostable reverse transcriptase enzymes (RT-CSR). Using this technique, a high-fidelity PCR enzyme was converted into a proofreading reverse transcriptase, yielding the world’s first high-fidelity reverse transcriptase, which has been patented and licensed for commercial production.